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What is cancer?

What we choose to eat is one of the factors involved in cancer risk.
It's estimated a third of cancers could be prevented by making healthier
food choices, being physically active and having a healthy body weight. 

Diet and heart disease: Cardiovascular disease (CVD)

Diet and heart diseaseCardiovascular disease (CVD), is a group of conditions that includes stroke and heart disease. CVD kills one in three people in the UK. While some contributing factors can't be altered, we can change our lifestyle.

CVD is caused by a build-up of fatty streaks and cholesterol in the blood vessels.

Natural wear and tear to blood vessels makes it easier for fatty cholesterol to leak in and get stuck to the artery walls. This build-up causes the arteries to narrow, reducing the heart's ability to pump blood through them to the body. If they become completely blocked, it will cause a heart attack or a stroke if the blockage occurs in the brain's blood vessels.

Importantly, not all cholesterol is bad. There are two types of cholesterol in the bloodstream: LDLs and HDLs. LDLs create the build-up in arteries, while high HDL levels are a good sign that you're not at risk of CVD.

Preventing cells from getting the kinks out of DNA

Preventing cells from getting the kinks out of DNA Many standard antibiotics and anti-cancer drugs block the enzymes that snip the kinks and knots out of DNA — DNA tangles are lethal to cells — but the drugs are increasingly encountering resistant bacteria and tumors.

A new discovery by University of California, Berkeley, biochemists could pave the way for new research into how to re-design these drugs to make them more effective poisons for cancer cells and harmful bacteria.

"The development of the anti-bacterial and anti-tumor agents that target these enzymes thus far has been done entirely in the absence of any visualization of how these drugs actually interact with the protein itself. And they have done remarkably well," said James Berger, UC Berkeley professor of molecular and cell biology. "But we have increasing problems of resistance to these drugs. Being able to see how these drugs can interact with the enzyme and DNA is going to be critical to developing the next generation of therapeutics that can be used to overcome these resistance problems."

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